Telomere Shortening and damage
It is thought that most of the diseases of old age
come about through cell senescence due to
Telomeres are the “caps” found
on the end of chromosomes in somatic cells.
Programmed Epigenomic Changes
Aging is a consequence of programmed shifts in
gene expression that happen throughout life.
Decline in Adult Stem Cell Differentiation
Aging is due to a slowing rate of organ
regeneration because of declining differentiation
activity of adult stem cells.
Major theories of aging
To see details click on title of theory